Welcome to the Johnstone Lab at UC Santa Cruz! We investigate the fundamental properties of biologically relevant inorganic compounds and apply them, in conjunction with biomaterials, to the solution of problems related to human health. Explore this site to learn more about our research, see recent publications, find out who is in the group, and discover links to other interesting resources. If you are interested in joining the lab or learning more about our chemistry, don’t hesitate to contact us.


2022-01-21 - The virtual PBSE visiting session draws to a close. A big thank you to all the prospective graduate students who attended and all the UCSC staff who worked so hard to make this event happen!

2022-01-19 - Our paper on the cyclodextrin encapsulation of dodecaiodododecaborate and its impact on hemolysis has been accepted in Chemical Communications as a part of the special issue "Boron Chemistry in the 21st Century." Congratulations Sophie!

2022-01-19 - Radcliff ends his rotation in the group and delivers a great PBSE rotation talk. Congratulations Radcliff!

2022-01-10 - Maria Sajimon begins rotating in the Johnstone Group. Welcome Maria!

2022-01-10 - Abram, an ACCESS alumus, rejoins the group as a UCSC undergraduate researcher. Welcome back Abram!

2021-12-08 - A paper describing a collaborative project with the Raskatov and Oliver groups at UCSC was accepted in Chemical Science. The paper describes the first high-resolution structure of a beta rippled sheet, which was first predicted by Pauling and Corey in 1953. Congratulations Ariel and Beatriz!

2021-11-30 - Sophie, Kevin, and Leila delivered their first-year rotation talks over the course of the past two days. All three of them did a great job over the course of the quarter and with their presentations. Congratulations to all three!

2021-11-23 - Viky Villanueva joins the Johnstone Group as an undergraduate researcher. Welcome Viky!

2021-11-15 - Radcliff Huffman starts his second PBSE rotation in the Johnstone Group. Welcome Radcliff!

2021-11-11 - Vivian Gallego joins the Johnstone Group as an undergraduate researcher. Welcome Vivian!

2021-10-29 - The group has fun parading around as Pokemon (with Tim as Ash!) for the Chemistry Department's annual Kenny Ikei Halloween Party. Many thanks as always to Ted Holman for organizing and for all the students, faculty, and staff that came out and had a great time!

2021-10-28 - Pumpkin carving, candy, pies, and crisp autumn air: the Johnstone Lab takes a moment to enjoy the season!

2021-10-18 - Our paper describing the single-crystal neutron diffraction, mulitpole refinement, and Hirsfeld Atom Refinement of a hydroxystibonium cation has been published in Inorganic Chemistry. Congratulations John! And particular thanks to Xiaoping Wang at Oak Ridge National Lab without whom the neutron diffraction work would not have been possible.

2021-09-23 - Leila Parker and Kevin Chou begin their chemistry rotations in the Lab for Fall Quarter. Welcome Leila and Kevin!

2021-09-20 - Brent is nominated by his peers to be the next Graduate Student Liaison for the Department of Chemistry and Biochemistry. Congratulations Brent!

2021-09-18 - Undergraduate alumnus Griffin Milligan is awarded the Doug Drexler Chemistry Scholarship and the Joseph F. Bunnett Undergraduate Research Prize for all his hard work at UCSC. Congratulations Griffin!

2021-09-17 - The 2021 Chemistry Fall Conference was a huge success! Many thanks to Sarah Loerch and Katie Cramton for all their hard work organizing. John gave a talk about his work on stibine oxides and Brent spoke about his work on pentaphenylantimony. Both talks were fantastic! Daniel and Alissa presented posters on their projects on carbon monoxide poisoning and nanoparticle delivery. Tim will be sure to make trivia easier next year... A very warm welcome to our incoming cohort of chemistry graduate students!

2021-09-13 - The Johnstone Lab had a great day at the 2021 PBSE Kick-off Event. Alissa, Brent, Daniel, and John presented a poster on the group's work - thanks to all who stopped by and a warm welcome to the incoming graduate cohort of 2021!. 

2021-08-25 - Our collaborative work with the Butler Group (University of California, Santa Barbara) on the chemistry of the newly discovered siderophore frederiksenibactin has been published in Chemical Science. Congratulations Parker!

2021-08-08 - Daniel is a recipient of one of the two 2020-2021 Outstanding TA Awards issued by the Department of Chemistry and Biochemistry. Congratulations Daniel! And many thanks to all of our TAs, who had to overcome so many extra difficulties with teaching this year.

2021-06-25 - Robert Jenkins joins the Johnstone Group as an undergraduate researcher. Welcome Roby!


2021-06-21 - Natalie Hemond from American River College and Abram Rodriguez from Gavilan College start their undergraduate summer research projects in the Johnstone Lab today. Welcome Natalie and Abram!

2021-06-07 - Tim presents the group's work on fundamental antimony chemistry at the University of Birmingham School of Chemistry Seminar Series. A big thanks to the department for the warm reception and to Profs. Andy Jupp and Sarah Pike for the invitation!

2021-06-04 - Our paper on the solution-state structure of pentaphenylantimony has been accepted in Inorg. Chem. This work would not have been possible without the XAS expertise of Prof. Graham George (University of Saskatchewan) and his team. Many thanks to them and congratulations Brent!

2021-05-28 - Alissa delivered her third-year seminar to the Department of Molecular, Cell, and Developmental Biology and has now advanced to PhD candidacy. Congratulations Alissa!

2021-05-24 - Daniel has been selected to receive a 2021-2022 ARCS Fellowship. Congratulation Daniel and thank you ARCS Foundation!

2021-05-05 - Sophie Hollow is profiled in the Department of Chemistry and Biochemistry's Undergraduate Student Spotlight. Congratulations Sophie!

2021-04-19 - Alissa successfully passed her MCDB Qualifying Exam. Congratulations Alissa!

2021-03-30 - Another Johnstone lab member joins the ranks of the UCSC PhD candidate cohort; congratulations to Daniels on passing his Qualifying Exam!

2021 -03-19 - Tim presents the group's work on understanding the structures of antimony-based drugs at the California State University, Sacramento. Chemistry Seminar Series. Many thanks to Prof. Ben Gherman for the invitation and hosting the seminar!

2021-03-19 - Sophie Hollow graduates with her Bachelors of Science degree. Congratulations Sophie!

2021-03-08 - The Johnstone group hosted the virtual visit of Prof. Mike Pluth from the University of Oregon, who delivered the departmental seminar this week. Thanks Mike for sharing all the great chemistry that you and your group are doing!

2021-03-02 - Brent successfully passed his third-year Qualifying Exam. Congratulations Brent!

2021-03-02 - Our paper on the reassignment of stibine oxides as hydroxystibonium cations has been accepted in Chem Comm. Congratulations John!

2021-01-20 - Our paper on pnictogen-oxygen bonding has been published in Inorganic Chemistry. Congratulations Brent and John!

2021-01-13 - John successfully delivers and defends his second-year seminar on main-group nitrogen fixation. Congratulations John!

2020-12-04 - Tim gives a talk to the UC Berkeley Nanosciences & Nanoengineering Institute on nanodelivery of inorganic drugs. Many thanks to Derek Popple and Avi Rosenzweig for the invitation!

2020-11-23 - Tim's work on using Frustrated Lewis Pair concepts to reinforce learning in undergraduate chemistry courses appears in the book Frustrated Lewis Pairs. Many thanks to Andy Jupp and Chris Slootweg for editing this volume and to the spring 2020 cohort of CHEM 151B for their help in generating the data!

2020-10-12 - Alissa Lance-Byrne joins as the newest graduate student member of the Johnstone Group. Welcome Alissa!

2020-09-25 - The Johnstone Lab attends the 2020 UCSC Chemistry Fall Conference, which Tim hosted. Thank you to all the students and post-docs who presented their research, Prof. Andy Borovik for being our keynote speaker, the graduate students who moderated the panel session, and all those who stayed for trivia! Also a big welcome to all of our new chemistry graduate students! 

2020-09-10 - The Johnstone Lab attends the annual PBSE Fall Research Conference, where Daniel and Brent present posters on their research. Welcome new PBSE grad students! 

2020-09-04 - The UC Cancer Research Coordinating Committee has awarded the Johnstone Lab a seed grant to investigate the use of arylarsonic acids to treat hematological cancers. Thank you to all the folks at UCOP and CRCC for this support!

2020-08-31 - Thanks to the efforts of CalFire, the blaze closest to campus is greatly contained and air quality has improved significantly. PSB has been cleared to reopen and lab work can recommence. Thank you to all who put themselves in harm's way to stop the spread of the fires!

2020-08-20 - The lab will be shutting down in compliance with the evacuation order enacted by the Chancellor on account of the wildfires. Stay safe everyone.

2020-08-17 - Daniel and Brent are (virtually) off to the Fall ACS National Meeting this week to present posters on their work. Good luck Brent and Daniel!

2020-08-15 - Sophie is given a 2020 Undergraduate Award in Inorganic Chemistry by the Division of Inorganic Chemistry of the ACS. Congratulations Sophie!

2020-07-22 - Our application to the NSF Major Research Instrumentation program for a new dual-source single-crystal X-ray diffractometer was funded! Thank you to the National Science Foundation, the UCSC Office of Research, the Division of Physical and Biological Sciences, and the Departments of Chemistry & Biochemistry and Earth & Planetary Sciences!  

2020-07-20 - John Wenger joins as the newest graduate student member of the Johnstone Group. Welcome John!

2020-06-08 - A collaborative study with the Goicoechea group at Oxford on a "push‐pull" phosphinidene stabilized by a β‐diketiminato ligand was published in Chemistry - A European Journal. Congratulations to all and we look forward to more fun science together in the future!

2020-06-02 - With our re-entry plan approved, the Johnstone Lab begins the process of gradually reopening!

2020-05-13 - Tim is selected from among the Hellman Fellows as the UCSC Featured Fellow by the Hellman Foundation. Thank you so much for your support!

2020-05-12 - A paper by Gabriella and Tim describing a tool to identify symmetry between groups of molecules was published in the Journal of Chemical Education. This work was made possible because of the UCSC CITL/DSS Faculty Fellowship. Thank you CITL and DSS, and congratulations Gabriella!

2020-04-14 - Tim is named one of the 2020 UCSC Hellman Fellows. The Hellman Foundation is generously supporting our work on carbon monoxide poisoning and antimony-based antiparasitic agents.

2020-03-25 - Brent successfully delivered and defended his (remote!) second year seminar on the use of arsenic-containing molecules to treat human African trypanosomiasis. Congratulations Brent!

2020-03-17 - The Johnstone Lab is officially going into temporary shutdown to observe the stay-at-home order and help stem the spread of COVID-19. Stay safe everyone!

2020-03-08 - The Johnstone Lab (notably Brent) completes its first synchrotron run at SSRL. Thanks to Graham George and his group for kindly bringing us on board!

2020-02-28 - The Johnstone Lab and the rest of the Department welcomes the prospective graduate students as they visit for their interviews. Enjoy your time in Santa Cruz and we hope to see you again soon!

2020-02-19 - Daniel successfully delivered and defended his second year seminar on the work that he has been doing on porphyrin-based antidotes for carbon monoxide poisoning. Congratulations Daniel!

2020-01-19 - Tim attends the 2020 Metals in Biology Gordon Research Conference and serves as a discussion leader for the medicinal inorganic chemistry session. Thanks to all speakers and attendees for a week filled with great science and stimulating discussion!

2019-11-18 - Austin Hopiavuori joins the Johnstone Lab as a PBSE rotation student. Welcome Austin!

2019-11-04 - The Johnstone Lab hosts Prof. Alison Butler from UC Santa Barbara. Faculty from across the department enjoyed being able to interact with Prof. Butler and she gave a wonderful seminar on her research. Thanks Alison!

2019-10-11 - Daniel welcomes a new addition to his family. All the best to him, Jess, and the newest little chemist on the block!

2019-09-20 - The 2019 Chemistry Fall Conference was a great success today! Tim helped to coordinate the event with Alex Ayzner and nothing would have happened without Katie Cramton. Many thanks to the Department of Chemistry & Biochemistry and our sponsors: Bruker, Quark, and VWR. A great day of science from students and our keynote speaker, Prof. Ken Raymond from UC Berkeley. 

2019-09-19 - Undergraduate Zach Davis returns after the Summer break. Welcome back!

2019-09-18 - Tim participates in the 2019 Teaching Academy hosted by the UCSC CITL. Tim's take on the event was featured in the UCSC News.

2019-09-11 - The Johnstone Lab enjoys a day at Roaring Camp for the 2019 PBSE Fall Research Conference. Many thanks to the organizers.

2019-09-03 - Indranil Chakraborty joins the group as a Research Specialist. Welcome to the lab and welcome back to UCSC!

2019-09-03 - Undergraduate Griffin Milligan joins the group. Welcome!

2019-08-13 - The Johnstone Group had its first birthday this past week! Mini celebration at this week's group meeting.

2019-07-01 - Undergraduate alumna Sakshi Soti begins her Masters in Biomedical Sciences at Western University of Health Sciences. Best of luck Sakshi!

2019-06-19 - Undergraduate Sophia Hollow joins the group. Welcome!

2019-06-16 - Gabriella Ruiz graduates with her Bachelors of Science degree. Congratulations Gabriella!

2019-04-27 - Tim attended to the table for the Department of Chemistry & Biochemistry along with Alex Ayzner and Katie Cramton at the Alumni Weekend event today. Thanks to all the alumni who came back into Santa Cruz to relive some memories!

2019-04-12 - The UCSC Committee on Research has awarded the Johnstone Group a New Faculty Research Grant to support our work on developing an antidote for carbon monoxide poisoning. Thank you for the support!

2019-03-15 - Tim completes the 2019 UCSC Leadership Academy. Many thanks to the Division of Academic Affairs for organizing this opportunity.

2019-02-07 - Tim serves as a judge at the Westlake Elementary School Science Fair. Congratulations to all the students who worked so hard on their fantastic projects!

2019-02-01 - The Chemistry Graduate Student Visit wrapped up today. We hope that the prospective students enjoyed their time in Santa Cruz and we look forward to seeing you here in the Fall!

2019-01-25 - PBSE graduate students Amanda Carbajal and Alissa Lance-Byrne will be rotating in the group. Welcome!

2019-01-15 - The UCSC Committee on Research has awarded the Johnstone Group a New Faculty Research Grant to support our work on the nanodelivery of antimony-based antileishmanial agents. Thank you for the support!


2019-01-14 - The Johnstone Group hosts Prof. Justin Wilson from Cornell University, who gave a fantastic seminar on his medicinal inorganic chemistry research program. Thanks for the science!

2019-01-01 - Graduate students Brent Lindquist-Kleissler and Daniel Droege officially join the group. Welcome!

2018-09-21 - Tim presents his past and proposed research to the department as part of the 2018 Chemistry Fall Conference. Lots of great science from students in the department and the keynote speaker, Prof. Louise Berben of UC Davis.

2018-09-13 - Undergraduates Gabriella Ruiz, Sakshi Soti, and Zach Davis join the group. Welcome!

2018-09-13 - Tim gives a presentation at the 2018 PBSE Fall Research Conference, talking to the incoming cohort about his proposed research. A full day of great science from across multiple departments!

2018-09-11 - Tim is named a Faculty Fellow of the UCSC Center for Innovation in Teaching and Learning (CITL). The fellowship is also supported by the UCSC Division of Student Success. He is excited to be a part of this community of individuals dedicated to teaching and learning on campus.

2018-08-10 - Tim arrives at UCSC to start his independent career.